This tip is for those of you who want to get a little closer to the code in your site.
For years, print designers have been using layouts that web designers couldn't. Take a look at this A List Apart article
http://www.alistapart.com/articles/settingtypeontheweb (referenced in the tool I will link soon) and you'll see what I mean.
Google has released Blueprint, "a CSS framework, which aims to cut down on your CSS development time. It gives you a solid CSS foundation to build your project on top of, with an easy-to-use grid, sensible typography, and even a stylesheet for printing."
You can find the project over at
http://code.google.com/p/blueprintcss/. Good luck, and have fun!